Identification and characterization of Loa loa antigens responsible for cross-reactivity with rapid diagnostic tests for lymphatic filariasis.

The Global Program to Eliminate Lymphatic Filariasis (LF) relies on rapid diagnostic tests (RDTs) to determine where annual mass drug administration for LF is required and when it can be stopped. These tests detect a Wuchereria bancrofti glycoprotein in the blood of infected persons via a carbohydra...

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Bibliographic Details
Main Authors: Marla I Hertz, Hugues Nana-Djeunga, Joseph Kamgno, Abdel Jelil Njouendou, Valerine Chawa Chunda, Samuel Wanji, Amy Rush, Peter U Fischer, Gary J Weil, Philip J Budge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006963