Microwave assisted synthesis, characterization and investigation of antibacterial activity of 3-(5-(substituted-phenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives

Microwave assisted synthesis, characterization and investigation of antibacterial activity of 3-(5-(substituted-phenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives

A variety of 3-(5-(substituted-phenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives 3a–j were synthesized through microwave assisted thermal annulation of corresponding α,β-unsaturated ketones (chalcones) 2a–j via hydrazinolysis. Chalcones 2a–j were prepared from 3-acetyl-coumarin 1 whi...

Full description

Bibliographic Details
Main Authors: Olayinka O. Ajani, Maria M. Akande, Natasha October, Tolutope O. Siyanbola, Damilola V. Aderohunmu, Anuoluwa A. Akinsiku, Shade J. Olorunshola
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Arab Journal of Basic and Applied Sciences
Subjects:
microwave synthesis
pyrazoline
coumarin motifs
antibacterial
gentamicin
Online Access:http://dx.doi.org/10.1080/25765299.2019.1632141

Internet

http://dx.doi.org/10.1080/25765299.2019.1632141

Similar Items