Identification of genome-scale metabolic network models using experimentally measured flux profiles.

Genome-scale metabolic network models can be reconstructed for well-characterized organisms using genomic annotation and literature information. However, there are many instances in which model predictions of metabolic fluxes are not entirely consistent with experimental data, indicating that the re...

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Bibliographic Details
Main Authors: Markus J Herrgård, Stephen S Fong, Bernhard Ø Palsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1487183?pdf=render