Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

Centrosomes are microtubule-nucleating organelles that facilitate chromosome segregation and cell division in metazoans. Centrosomes comprise centrioles that organize a micron-scale mass of protein called pericentriolar material (PCM) from which microtubules nucleate. During each cell cycle, PCM acc...

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Bibliographic Details
Main Authors: Stephen J. Enos, Martin Dressler, Beatriz Ferreira Gomes, Anthony A. Hyman, Jeffrey B. Woodruff
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Biology Open
Subjects:
Centrosome
Disassembly
Phosphatase PP2A
SPD-5
LET-92
Pericentriolar material
Online Access:http://bio.biologists.org/content/7/1/bio029777

Internet

http://bio.biologists.org/content/7/1/bio029777

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