Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas.

Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas.

Patients with germline AIP mutations or low AIP protein expression have large, invasive somatotroph adenomas and poor response to somatostatin analogues (SSA).To study the mechanism of low AIP protein expression 31 sporadic somatotropinomas with low (n = 13) or high (n = 18) AIP protein expression w...

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Bibliographic Details
Main Authors: Judit Dénes, Leandro Kasuki, Giampaolo Trivellin, Leandro M Colli, Christina M Takiya, Craig E Stiles, Sayka Barry, Margaret de Castro, Mônica R Gadelha, Márta Korbonits
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319742?pdf=render

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http://europepmc.org/articles/PMC4319742?pdf=render

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