Diagnostic delay of pediatric inflammatory bowel disease in Saudi Arabia

• Main Authors: Mohammad I El Mouzan, Badr I AlSaleem, Mohammed Y Hasosah, Abdulrahman A Al-Hussaini, Aziz H Al Anazi, Omar I Saadah, Ahmed A Al Sarkhy, Mohammad A Al Mofarreh, Asaad A Assiri
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2019-01-01
• Series: The Saudi Journal of Gastroenterology
• Subjects: Crohn's disease; diagnostic delay; ulcerative colitis
• Online Access: http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2019;volume=25;issue=4;spage=257;epage=261;aulast=El

Background/Aim: Delay in the diagnosis of inflammatory bowel disease (IBD) is associated with complications. Our aim was to describe the pattern and risk factors associated with delay in the diagnosis of IBD in Saudi children. Patients and Methods: This was a multicenter study with a retrospective/prospective design. Data on diagnostic delay in children with Crohn's disease (CD) and ulcerative colitis (UC) were retrieved from physician's notes. Multivariate regression analysis was used to assess the risk factors associated with long delay in diagnosis. Results: There were 240 and 183 Saudi children with CD and UC, respectively. The median delays in diagnosis were 8 and 5 months in CD and UC, respectively, significantly longer in children with CD than UC (P < 0.001). Long diagnostic delays (>75th percentile) were 24 and 8.8 months for CD and UC, respectively. Ileal location was a significant risk factor in CD and the age of onset above 10 years was protective in UC. Conclusions: Long diagnostic delay in IBD was mainly due to the longer delay in gastroenterologist consultation. Review of the referral system is needed to focus on measures to reduce long delays in diagnosis. The ileal location as a risk factor in CD and age older than 10 years as protective in UC should help recognition and early referral.