Mapping the spatio-temporal pattern of the mammalian target of rapamycin (mTOR) activation in temporal lobe epilepsy.

Growing evidence from rodent models of temporal lobe epilepsy (TLE) indicates that dysregulation of the mammalian target of rapamycin (mTOR) pathway is involved in seizures and epileptogenesis. However, the role of the mTOR pathway in the epileptogenic process remains poorly understood. Here, we use...

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Bibliographic Details
Main Authors: Long-Ze Sha, Xiao-Liang Xing, Dan Zhang, Yuan Yao, Wan-Chen Dou, Li-Ri Jin, Li-Wen Wu, Qi Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3384628?pdf=render