Design, Synthesis and Characterization of Novel Co-Polymers Decorated with Peptides for the Selective Nanoparticle Transport across the Cerebral Endothelium

Design, Synthesis and Characterization of Novel Co-Polymers Decorated with Peptides for the Selective Nanoparticle Transport across the Cerebral Endothelium

The development of new strategies for enhancing drug delivery to the brain represents a major challenge in treating cerebral diseases. In this paper, we report on the synthesis and structural characterization of a biocompatible nanoparticle (NP) made up of poly(lactic-co-glycolic acid) (PLGA)-polyet...

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Bibliographic Details
Main Authors: Andrea P. Falanga, Pietro Melone, Roberta Cagliani, Nicola Borbone, Stefano D’Errico, Gennaro Piccialli, Paolo A. Netti, Daniela Guarnieri
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
nanoparticles
peptides
blood-brain barrier
drug delivery
transport
Online Access:http://www.mdpi.com/1420-3049/23/7/1655

Internet

http://www.mdpi.com/1420-3049/23/7/1655

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