Modeling of the Human Bone Environment: Mechanical Stimuli Guide Mesenchymal Stem Cell–Extracellular Matrix Interactions

In bone tissue engineering, the design of in vitro models able to recreate both the chemical composition, the structural architecture, and the overall mechanical environment of the native tissue is still often neglected. In this study, we apply a bioreactor system where human bone-marrow hMSCs are s...

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Bibliographic Details
Main Authors: Ana Rita Pereira, Andreas Lipphaus, Mert Ergin, Sahar Salehi, Dominic Gehweiler, Maximilian Rudert, Jan Hansmann, Marietta Herrmann
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/14/16/4431