Hypervalent Iodine-Mediated Diastereoselective α-Acetoxylation of Cyclic Ketones

Hypervalent Iodine-Mediated Diastereoselective α-Acetoxylation of Cyclic Ketones

A binary hybrid system comprising a hypervalent iodine(III) reagent and BF3•OEt2 Lewis acid was found to be effective for the diastereoselective α-acetoxylation of cyclic ketones. In this hybrid system, BF3•OEt2 Lewis acid allowed the activation of the hypervalent iodine(III) reagent and cyclic keto...

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Bibliographic Details
Main Authors: Jiashen Tan, Weiqin Zhu, Weiping Xu, Yaru Jing, Zhuofeng Ke, Yan Liu, Keiji Maruoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Chemistry
Subjects:
α-acetoxylation
hypervalent iodine (III) reagent
cyclic ketones
diastereoselectivity
density functional theory
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00467/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00467/full

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