Nonalcoholic Fatty Liver Disease Impairs the Liver–Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

Nonalcoholic Fatty Liver Disease Impairs the Liver–Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

Nonalcoholic fatty liver disease (NAFLD) is associated with impaired hepatic actions of glucagon and insulin. Glucagon and amino acids are linked in an endocrine feedback circuit, the liver–alpha cell axis, that may be disrupted by NAFLD. We investigated how NAFLD severity affects glucagon and insul...

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Bibliographic Details
Main Authors: Julie Steen Pedersen, Marte Opseth Rygg, Viggo Bjerregaard Kristiansen, Beth Hærstedt Olsen, Reza Rafiolsadat Serizawa, Jens Juul Holst, Sten Madsbad, Lise Lotte Gluud, Flemming Bendtsen, Nicolai Jacob Wewer Albrechtsen
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1562

Internet

https://doi.org/10.1002/hep4.1562

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