DDS promotes longevity through a microbiome-mediated starvation signal
The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in Caenorhabditis elegans through inhibition of pyruvate kinase and decreased mitochondrial function. Here we report a...
Main Authors: | Haeri Choi, Sung Chun Cho, Young Wan Ha, Billie Ocampo, Shirley Park, Shiwen Chen, Christopher F. Bennett, Jeehae Han, Ryan Rossner, Jong-Sun Kang, Yun-ll Lee, Sang Chul Park, Matt Kaeberlein |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2019-01-01
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Series: | Translational Medicine of Aging |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468501119300045 |
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