Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals.

Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals.

There is great interindividual variability in HIV-1 viral setpoint after seroconversion, some of which is known to be due to genetic differences among infected individuals. Here, our focus is on determining, genome-wide, the contribution of variable gene expression to viral control, and to relate it...

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Bibliographic Details
Main Authors: Margalida Rotger, Kristen K Dang, Jacques Fellay, Erin L Heinzen, Sheng Feng, Patrick Descombes, Kevin V Shianna, Dongliang Ge, Huldrych F Günthard, David B Goldstein, Amalio Telenti, Swiss HIV Cohort Study, Center for HIV/AIDS Vaccine Immunology
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2829051?pdf=render

Internet

http://europepmc.org/articles/PMC2829051?pdf=render

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