Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue

Serum paraoxonase 1 (PON1) function has been associated with human cardiovascular disease. The projected mechanism postulates interaction of PON1 with lipoproteins and insulin signaling resulting in alterations in lipid homeostasis. Recently, PON2 was shown to directly regulate triglyceride accumula...

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Bibliographic Details
Main Authors: Alexandros Zafiropoulos, Manolis Linardakis, Eugene H.J.M. Jansen, Aristidis M. Tsatsakis, Antonis Kafatos, George N. Tzanakakis
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520371212