A modified chronic infection model for testing treatment of Staphylococcus aureus biofilms on implants.

Bacterial biofilms causing implant-associated osteomyelitis is a severe complication with limited antimicrobial therapy options. We designed an animal model, in which implant associated osteomyelitis arise from a Staphylococcus aureus biofilm on a tibia implant. Two bioluminescently engineered (luxA...

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Bibliographic Details
Main Authors: Nis Pedersen Jørgensen, Rikke L Meyer, Frederik Dagnæs-Hansen, Kurt Fuursted, Eskild Petersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4184782?pdf=render