Overexpression of microRNA-216a-3p Accelerates the Inflammatory Response in Cardiomyocytes in Type 2 Diabetes Mellitus by Targeting IFN-α2

Overexpression of microRNA-216a-3p Accelerates the Inflammatory Response in Cardiomyocytes in Type 2 Diabetes Mellitus by Targeting IFN-α2

Background: Type 2 diabetes mellitus (T2DM) is a chronic, hyperglycemia-associated, metabolic disorder. Heart disease is a major complication of T2DM. The present study aimed to explore the effects of miR-216a-3p on cardiomyocyte proliferation, apoptosis, and inflammation in T2DM through the Toll-li...

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Bibliographic Details
Main Authors: Xiaomeng Liu, Yusong Zhang, Hongwei Liang, Yanchao Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
microRNA-216a-3p
interferon-α2
Toll-like receptor signaling pathway
type 2 diabetes mellitus
cardiomyocytes
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.522340/full

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https://www.frontiersin.org/articles/10.3389/fendo.2020.522340/full

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