Steric exclusion and protein conformation determine the localization of plasma membrane transporters

The yeast plasma membrane consists of membrane microdomains with distinct protein composition. Here the authors use high-resolution single molecule imaging to observe diffusion of specific transmembrane proteins in and out of these microdomains, and propose features that dictate their inclusion/excl...

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Bibliographic Details
Main Authors: Frans Bianchi, Łukasz Syga, Gemma Moiset, Dian Spakman, Paul E. Schavemaker, Christiaan M. Punter, Anne-Bart Seinen, Antoine M. van Oijen, Andrew Robinson, Bert Poolman
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02864-2