Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis

BACKGROUND: CpG island methylator phenotype (CIMP) tumors, comprising 20% of colorectal cancers, are associated with female sex, age, right-sided location, and BRAF mutations. However, other factors potentially associated with CIMP have not been robustly examined. This meta-analysis provides a compr...

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Main Authors: Shailesh M. Advani, Pragati Advani, Stacia M. DeSantis, Derek Brown, Helena M. VonVille, Michael Lam, Jonathan M. Loree, Amir Mehrvarz Sarshekeh, Jan Bressler, David S. Lopez, Carrie R. Daniel, Michael D. Swartz, Scott Kopetz
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523318301499