Understanding reduced rotavirus vaccine efficacy in low socio-economic settings.

Rotavirus vaccine efficacy ranges from >90% in high socio-economic settings (SES) to 50% in low SES. With the imminent introduction of rotavirus vaccine in low SES countries, understanding reasons for reduced efficacy in these settings could identify strategies to improve vaccine performance.We d...

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Bibliographic Details
Main Authors: Benjamin A Lopman, Virginia E Pitzer, Rajiv Sarkar, Beryl Gladstone, Manish Patel, John Glasser, Manoj Gambhir, Christina Atchison, Bryan T Grenfell, W John Edmunds, Gagandeep Kang, Umesh D Parashar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412858?pdf=render