PTEN is a negative regulator of mitotic checkpoint complex during the cell cycle

PTEN is a negative regulator of mitotic checkpoint complex during the cell cycle

Abstract Nuclear PTEN plays an important role during mitosis. To understand the molecular basis by which PTEN mediates mitotic progression, we examined whether PTEN regulated the formation of mitotic checkpoint complex (MCC). We observed that arsenic trioxide, a mitotic inducer, stimulated nuclear t...

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Bibliographic Details
Main Authors: Byeong H. Choi, Steve Xie, Wei Dai
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Experimental Hematology & Oncology
Subjects:
PTEN
Mitosis
Mitotic checkpoint complex
Nuclear localization
Chromosomes
Online Access:http://link.springer.com/article/10.1186/s40164-017-0079-0

Internet

http://link.springer.com/article/10.1186/s40164-017-0079-0

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