Knockdown of UTX/KDM6A Enriches Precursor Cell Populations in Urothelial Cell Cultures and Cell Lines
The histone demethylase UTX (gene: <i>KDM6A</i>) directs cell and tissue differentiation during development. Deleterious mutations in <i>KDM6A</i> occur in many human cancers, most frequently in urothelial carcinoma. The consequences of these mutations are poorly understood;...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/4/1023 |