Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data.

Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an inference method based on the joint frequency spectrum of genetic variants within and between populations. For candidate mode...

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Bibliographic Details
Main Authors: Ryan N Gutenkunst, Ryan D Hernandez, Scott H Williamson, Carlos D Bustamante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2760211?pdf=render