Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial

Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial

Abstract Background Prior studies in critically ill patients suggest the supra-physiologic chloride concentration of 0.9% (“normal”) saline may be associated with higher risk of renal failure and death compared to physiologically balanced crystalloids. However, the comparative effects of 0.9% saline...

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Bibliographic Details
Main Authors: Wesley H. Self, Matthew W. Semler, Jonathan P. Wanderer, Jesse M. Ehrenfeld, Daniel W. Byrne, Li Wang, Leanne Atchison, Matthew Felbinger, Ian D. Jones, Stephan Russ, Andrew D. Shaw, Gordon R. Bernard, Todd W. Rice
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Trials
Subjects:
Intravenous fluids
Crystalloid
Saline
Renal failure
Pragmatic trial
Emergency department
Online Access:http://link.springer.com/article/10.1186/s13063-017-1923-6

Internet

http://link.springer.com/article/10.1186/s13063-017-1923-6

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