Assessment of paclitaxel induced sensory polyneuropathy with "Catwalk" automated gait analysis in mice.

Neuropathic pain as a symptom of sensory nerve damage is a frequent side effect of chemotherapy. The most common behavioral observation in animal models of chemotherapy induced polyneuropathy is the development of mechanical allodynia, which is quantified with von Frey filaments. The data from one s...

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Bibliographic Details
Main Authors: Petra Huehnchen, Wolfgang Boehmerle, Matthias Endres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3797113?pdf=render