Modeling statin myopathy in a human skeletal muscle microphysiological system.

Statins are used to lower cholesterol and prevent cardiovascular disease. Musculoskeletal side effects known as statin associated musculoskeletal symptoms (SAMS), are reported in up to 10% of statin users, necessitating statin therapy interruption and increasing cardiovascular disease risk. We teste...

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Bibliographic Details
Main Authors: Anandita Ananthakumar, Yiling Liu, Cristina E Fernandez, George A Truskey, Deepak Voora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242422