No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis

No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis

Abstract Background The Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers Aβ1–42, t-tau, and p-tau181 overlap with other diseases. New tau modifications or epitopes, such as the non-phosphorylated tau fraction (p-taurel), may improve differential dementia diagnosis. The goal of this stud...

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Bibliographic Details
Main Authors: Joery Goossens, Maria Bjerke, Hanne Struyfs, Ellis Niemantsverdriet, Charisse Somers, Tobi Van den Bossche, Sara Van Mossevelde, Bart De Vil, Anne Sieben, Jean-Jacques Martin, Patrick Cras, Johan Goeman, Peter Paul De Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Differential diagnosis
Cerebrospinal fluid
Biomarkers
Tau
Frontotemporal lobar degeneration
Online Access:http://link.springer.com/article/10.1186/s13195-017-0275-5

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http://link.springer.com/article/10.1186/s13195-017-0275-5

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