Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer

Expression of immune checkpoints on circulating tumor cells in men with metastatic prostate cancer

Abstract Background A subset of men with metastatic prostate cancer (mPC) responds to immune checkpoint inhibitors, and there is an unmet need to predict those most likely to benefit. We characterized circulating tumor cells (CTCs) for expression of immune checkpoint ligands in men with mPC as a non...

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Bibliographic Details
Main Authors: Tian Zhang, Anika Agarwal, R. Garland Almquist, Daniella Runyambo, Sally Park, Elizabeth Bronson, Rengasamy Boominathan, Chandra Rao, Monika Anand, Taofik Oyekunle, Patrick Healy, Megan A. McNamara, Kathryn Ware, Jason A. Somarelli, Daniel J. George, Andrew J. Armstrong
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Biomarker Research
Subjects:
Circulating tumor cells
Metastatic prostate cancer
PD-L1
PD-L2
CTLA-4
Online Access:https://doi.org/10.1186/s40364-021-00267-y

Internet

https://doi.org/10.1186/s40364-021-00267-y

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