Intra-articular fms-like tyrosine kinase 3 ligand expression is a driving force in induction and progression of arthritis.

Intra-articular fms-like tyrosine kinase 3 ligand expression is a driving force in induction and progression of arthritis.

BACKGROUND: One of the hallmarks of rheumatoid arthritis (RA) is hyperplasia and inflammation of the synovial tissue being characterized by in situ occurrence of highly differentiated leukocytes. Fms-like tyrosine kinase 3 (Flt3) has a crucial role in hematopoiesis, regulation of cell proliferation,...

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Bibliographic Details
Main Authors: Mats Dehlin, Maria Bokarewa, Robert Rottapel, Simon J Foster, Mattias Magnusson, Leif E Dahlberg, Andrej Tarkowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2575855?pdf=render

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http://europepmc.org/articles/PMC2575855?pdf=render

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