LY293111 Improves Efficacy of Gemcitabine Therapy on Pancreatic Cancer in a Fluorescent Orthotopic Model in Athymic Mice
Pancreatic cancer has an abysmal prognosis because of late diagnosis and lack of effective therapeutics. New drugs are desperately needed. The present study determined the effect of the LTB4 receptor antagonist, LY293111, on tumor growth and metastases in a fluorescent orthotopic model of pancreati...
Main Authors: | Rene Hennig, Jacinthe Ventura, Ralf Segersvard, Erin Ward, Xian-Zhong Ding, Sambasiva M. Rao, Borko D. Jovanovic, Takeshi Iwamura, Mark S. Talamonti, Richard H. Bell Jr., Thomas E. Adrian |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2005-04-01
|
Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558605800739 |
Similar Items
-
The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model
by: Kentaro Miyake, et al.
Published: (2019-09-01) -
Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d
by: Takashi Semba, et al.
Published: (2020-12-01) -
A Novel Alkylating Agent, Glufosfamide, Enhances the Activity of Gemcitabine In Vitro, In Vivo
by: W. Steve Ammons, et al.
Published: (2007-08-01) -
LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model
by: Sadia Mehdi, et al.
Published: (2020-07-01) -
Tissue distribution of crizotinib and gemcitabine combination in a patient-derived orthotopic mouse model of pancreatic cancer
by: Richard J. Honeywell, et al.
Published: (2016-12-01)