PKCδ Mediates NF-<i>κ</i>B Inflammatory Response and Downregulates SIRT1 Expression in Liver Fibrosis

The precise mechanism of hepatic cirrhosis remains largely unclear. In particular, a potential regulatory mechanism by which protein kinase C-delta (PKC<i>&#948;</i> ) affects profibrogenic gene expression involved in hepatic cirrhosis has never been explored. In the present study, w...

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Bibliographic Details
Main Authors: Su Jin Lee, Su Ji Kim, Hyun-Shik Lee, Oh-Shin Kwon
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/18/4607