“Immune TOR-opathies,” a Novel Disease Entity in Clinical Immunology
Primary immunodeficiencies (PIDs) represent a group of mostly monogenic disorders caused by loss- or gain-of-function mutations in over 340 known genes that lead to abnormalities in the development and/or the function of the immune system. However, mutations in different genes can affect the same ce...
Main Authors: | Sophie Jung, Laura Gámez-Díaz, Michele Proietti, Bodo Grimbacher |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-05-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2018.00966/full |
Similar Items
-
mTOR signaling pathway and mTOR inhibitors in the treatment of cancer
by: Mehmet Küçüköner, et al.
Published: (2013-03-01) -
Novel Library of Selenocompounds as Kinase Modulators
by: Carmen Sanmartín, et al.
Published: (2011-07-01) -
The Role of mTOR Signaling as a Therapeutic Target in Cancer
by: Nadezhda V. Popova, et al.
Published: (2021-02-01) -
Targeting PI3K/Akt/mTOR Signaling In Cancer
by: Camillo ePorta, et al.
Published: (2014-04-01) -
AKTivation of the PI3K/AKT/mTOR signaling pathway by KSHV
by: Aadra P Bhatt, et al.
Published: (2013-01-01)