Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

<p>Abstract</p> <p>Background</p> <p>Pim family kinases are small constitutively active serine/threonine-specific kinases, elevated levels of which have been detected in human hematopoietic malignancies as well as in solid tumours. While we and others have previously sh...

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Bibliographic Details
Main Authors: Prudhomme Michelle, Virtanen Sanna S, Sandholm Jouko A, Rainio Eeva-Marja, Vahakoski Riitta L, Santio Niina M, Anizon Fabrice, Moreau Pascale, Koskinen Päivi J
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/279