Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique

We report on the fabrication of thin coatings based on polylactic acid-chitosan-magnetite-eugenol (PLA-CS-Fe3O4@EUG) nanospheres by matrix assisted pulsed laser evaporation (MAPLE). Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) investigation proved that the homogenous...

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Main Authors:	Alina Maria Holban, Valentina Grumezescu, Alexandru Mihai Grumezescu, Bogdan Ştefan Vasile, Roxana Truşcă, Rodica Cristescu, Gabriel Socol, Florin Iordache
Format:	Article
Language:	English
Published:	Beilstein-Institut 2014-06-01
Series:	Beilstein Journal of Nanotechnology
Subjects:	antimicrobial chitosan magnetite nanoparticles nanospheres P. aeruginosa polylactic acid S. aureus
Online Access:	https://doi.org/10.3762/bjnano.5.99

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spelling	doaj-75470cfd562341e1bf98e2f1ac2343d02020-11-24T23:14:19ZengBeilstein-InstitutBeilstein Journal of Nanotechnology2190-42862014-06-015187288010.3762/bjnano.5.992190-4286-5-99Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser techniqueAlina Maria Holban0Valentina Grumezescu1Alexandru Mihai Grumezescu2Bogdan Ştefan Vasile3Roxana Truşcă4Rodica Cristescu5Gabriel Socol6Florin Iordache7University of Bucharest, Faculty of Biology, Microbiology Department, Aleea Portocalelor no 1–3, 060101 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, Polizu Street no 1–7, 011061 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, Polizu Street no 1–7, 011061 Bucharest, RomaniaUniversity Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, Polizu Street no 1–7, 011061 Bucharest, RomaniaS.C. Metav-CD S.A., 31 Rosetti Str., 020015 Bucharest, RomaniaNational Institute for Lasers, Plasma & Radiation Physics, Lasers Department, P.O.Box MG-36, Bucharest-Magurele, RomaniaNational Institute for Lasers, Plasma & Radiation Physics, Lasers Department, P.O.Box MG-36, Bucharest-Magurele, RomaniaFlow Cytometry and Cell Therapy Laboratory, Institute of Cellular Biology and Pathology “Nicolae Simionescu” (ICBP), Bucharest, RomaniaWe report on the fabrication of thin coatings based on polylactic acid-chitosan-magnetite-eugenol (PLA-CS-Fe3O4@EUG) nanospheres by matrix assisted pulsed laser evaporation (MAPLE). Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) investigation proved that the homogenous Fe3O4@EUG nanoparticles have an average diameter of about 7 nm, while the PLA-CS-Fe3O4@EUG nanospheres diameter sizes range between 20 and 80 nm. These MAPLE-deposited coatings acted as bioactive nanosystems and exhibited a great antimicrobial effect by impairing the adherence and biofilm formation of Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) bacteria strains. Moreover, the obtained nano-coatings showed a good biocompatibility and facilitated the normal development of human endothelial cells. These nanosystems may be used as efficient alternatives in treating and preventing bacterial infections.https://doi.org/10.3762/bjnano.5.99antimicrobialchitosanmagnetite nanoparticlesnanospheresP. aeruginosapolylactic acidS. aureus
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Alina Maria Holban Valentina Grumezescu Alexandru Mihai Grumezescu Bogdan Ştefan Vasile Roxana Truşcă Rodica Cristescu Gabriel Socol Florin Iordache
spellingShingle	Alina Maria Holban Valentina Grumezescu Alexandru Mihai Grumezescu Bogdan Ştefan Vasile Roxana Truşcă Rodica Cristescu Gabriel Socol Florin Iordache Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique Beilstein Journal of Nanotechnology antimicrobial chitosan magnetite nanoparticles nanospheres P. aeruginosa polylactic acid S. aureus
author_facet	Alina Maria Holban Valentina Grumezescu Alexandru Mihai Grumezescu Bogdan Ştefan Vasile Roxana Truşcă Rodica Cristescu Gabriel Socol Florin Iordache
author_sort	Alina Maria Holban
title	Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique
title_short	Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique
title_full	Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique
title_fullStr	Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique
title_full_unstemmed	Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique
title_sort	antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique
publisher	Beilstein-Institut
series	Beilstein Journal of Nanotechnology
issn	2190-4286
publishDate	2014-06-01
description	We report on the fabrication of thin coatings based on polylactic acid-chitosan-magnetite-eugenol (PLA-CS-Fe3O4@EUG) nanospheres by matrix assisted pulsed laser evaporation (MAPLE). Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) investigation proved that the homogenous Fe3O4@EUG nanoparticles have an average diameter of about 7 nm, while the PLA-CS-Fe3O4@EUG nanospheres diameter sizes range between 20 and 80 nm. These MAPLE-deposited coatings acted as bioactive nanosystems and exhibited a great antimicrobial effect by impairing the adherence and biofilm formation of Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) bacteria strains. Moreover, the obtained nano-coatings showed a good biocompatibility and facilitated the normal development of human endothelial cells. These nanosystems may be used as efficient alternatives in treating and preventing bacterial infections.
topic	antimicrobial chitosan magnetite nanoparticles nanospheres P. aeruginosa polylactic acid S. aureus
url	https://doi.org/10.3762/bjnano.5.99
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Antimicrobial nanospheres thin coatings prepared by advanced pulsed laser technique

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