A versatile technique for the in vivo imaging of human tumor xenografts using near-infrared fluorochrome-conjugated macromolecule probes.

Here, we present a versatile method for detecting human tumor xenografts in vivo, based on the enhanced permeability and retention (EPR) effect, using near-infrared (NIR) fluorochrome-conjugated macromolecule probes. Bovine serum albumin (BSA) and two immunoglobulins-an anti-human leukocyte antigen...

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Bibliographic Details
Main Authors: Hiroshi Suemizu, Kenji Kawai, Yuichiro Higuchi, Haruo Hashimoto, Tomoyuki Ogura, Toshio Itoh, Erika Sasaki, Masato Nakamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866180?pdf=render