Enhancing TB case detection: experience in offering upfront Xpert MTB/RIF testing to pediatric presumptive TB and DR TB cases for early rapid diagnosis of drug sensitive and drug resistant TB.

BACKGROUND:Diagnosis of pulmonary tuberculosis (PTB) in children is challenging due to difficulties in obtaining good quality sputum specimens as well as the paucibacillary nature of disease. Globally a large proportion of pediatric tuberculosis (TB) cases are diagnosed based only on clinical findin...

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Main Authors: Neeraj Raizada, Kuldeep Singh Sachdeva, Sreenivas Achuthan Nair, Shubhangi Kulsange, Radhey Shayam Gupta, Rahul Thakur, Malik Parmar, Christen Gray, Ranjani Ramachandran, Bhavin Vadera, Shobha Ekka, Shikha Dhawan, Ameet Babre, Mayank Ghedia, Umesh Alavadi, Puneet Dewan, Mini Khetrapal, Ashwini Khanna, Catharina Boehme, Chinnambedu Nainarappan Paramsivan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4139368?pdf=render