CD44v6 as innovative sarcoma target for CAR-redirected CIK cells

CD44v6 as innovative sarcoma target for CAR-redirected CIK cells

Purpose of our study was to explore a new immunotherapy for high grade soft tissue sarcomas (STS) based on cytokine-induced killer cells (CIK) redirected with a chimeric antigen receptor (CAR) against the tumor-promoting antigen CD44v6. We aimed at generating bipotential killers, combining the CAR s...

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Bibliographic Details
Main Authors: V. Leuci, M. Casucci, G. Grignani, R. Rotolo, U. Rossotti, E. Vigna, L. Gammaitoni, G. Mesiano, E. Fiorino, C. Donini, A. Pisacane, L. D. ambrosio, Y. Pignochino, M. Aglietta, A. Bondanza, D. Sangiolo
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:OncoImmunology
Subjects:
cik
soft tissue sarcoma
cd44v6
car
adoptive immunotherapy
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1423167

Internet

http://dx.doi.org/10.1080/2162402X.2017.1423167

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