Challenges in the development of an immunochromatographic interferon-gamma test for diagnosis of pleural tuberculosis.

Existing diagnostic tests for pleural tuberculosis (TB) have inadequate accuracy and/or turnaround time. Interferon-gamma (IFNg) has been identified in many studies as a biomarker for pleural TB. Our objective was to develop a lateral flow, immunochromatographic test (ICT) based on this biomarker an...

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Bibliographic Details
Main Authors: Claudia M Denkinger, Yatiraj Kalantri, Samuel G Schumacher, Joy S Michael, Deepa Shankar, Arvind Saxena, Natarajan Sriram, Thangakunam Balamugesh, Robert Luo, Nira R Pollock, Madhukar Pai, Devasahayam J Christopher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3871622?pdf=render