High Levels of Epstein–Barr Virus Nuclear Antigen-1-Specific Antibodies and Infectious Mononucleosis Act Both Independently and Synergistically to Increase Multiple Sclerosis Risk

High Levels of Epstein–Barr Virus Nuclear Antigen-1-Specific Antibodies and Infectious Mononucleosis Act Both Independently and Synergistically to Increase Multiple Sclerosis Risk

Objective: Elevated levels of anti-EBNA-1 antibodies and infectious mononucleosis (IM) history have consistently been associated with multiple sclerosis (MS) risk. We aimed to study whether these aspects of Epstein–Barr virus (EBV) infection represent separate risk factors for MS and whether they bo...

Full description

Bibliographic Details
Main Authors: Anna Karin Hedström, Jesse Huang, Angelica Michel, Julia Butt, Nicole Brenner, Jan Hillert, Tim Waterboer, Ingrid Kockum, Tomas Olsson, Lars Alfredsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
Epstein–Barr virus infection
anti-EBNA-1 antibodies
infectious mononucleosis
human leukocyte antigen
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01368/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01368/full

Similar Items