Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia
Pneumocystis pneumonia (PCP) caused by the opportunistic fungal agent Pneumocystis jirovecii (formerly Pneumocystis carinii) continues to cause illness and death in HIV-infected patients. In the absence of a culture system to isolate and maintain live organisms, efforts to type and characterize the...
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Centers for Disease Control and Prevention
2004-10-01
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doaj-7728bce31e12446693abaa2fc4ee11b12020-11-25T02:29:17ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592004-10-0110101729173510.3201/eid1010.030981Strain Typing Methods and Molecular Epidemiology of Pneumocystis PneumoniaCharles Ben BeardPatricia RouxGilles NevezPhilippe M. HauserJoseph A. KovacsThomas R. UnnaschBettina LundgrenPneumocystis pneumonia (PCP) caused by the opportunistic fungal agent Pneumocystis jirovecii (formerly Pneumocystis carinii) continues to cause illness and death in HIV-infected patients. In the absence of a culture system to isolate and maintain live organisms, efforts to type and characterize the organism have relied on polymerase chain reaction–based approaches. Studies using these methods have improved understanding of PCP epidemiology, shedding light on sources of infection, transmission patterns, and potential emergence of antimicrobial resistance. One concern, however, is the lack of guidance regarding the appropriateness of different methods and standardization of these methods, which would facilitate comparing results reported by different laboratories.https://wwwnc.cdc.gov/eid/article/10/10/03-0981_articlePneumocystisPCPmolecular epidemiologytyping methodsperspective |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Charles Ben Beard Patricia Roux Gilles Nevez Philippe M. Hauser Joseph A. Kovacs Thomas R. Unnasch Bettina Lundgren |
spellingShingle |
Charles Ben Beard Patricia Roux Gilles Nevez Philippe M. Hauser Joseph A. Kovacs Thomas R. Unnasch Bettina Lundgren Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia Emerging Infectious Diseases Pneumocystis PCP molecular epidemiology typing methods perspective |
author_facet |
Charles Ben Beard Patricia Roux Gilles Nevez Philippe M. Hauser Joseph A. Kovacs Thomas R. Unnasch Bettina Lundgren |
author_sort |
Charles Ben Beard |
title |
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia |
title_short |
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia |
title_full |
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia |
title_fullStr |
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia |
title_full_unstemmed |
Strain Typing Methods and Molecular Epidemiology of Pneumocystis Pneumonia |
title_sort |
strain typing methods and molecular epidemiology of pneumocystis pneumonia |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2004-10-01 |
description |
Pneumocystis pneumonia (PCP) caused by the opportunistic fungal agent Pneumocystis jirovecii (formerly Pneumocystis carinii) continues to cause illness and death in HIV-infected patients. In the absence of a culture system to isolate and maintain live organisms, efforts to type and characterize the organism have relied on polymerase chain reaction–based approaches. Studies using these methods have improved understanding of PCP epidemiology, shedding light on sources of infection, transmission patterns, and potential emergence of antimicrobial resistance. One concern, however, is the lack of guidance regarding the appropriateness of different methods and standardization of these methods, which would facilitate comparing results reported by different laboratories. |
topic |
Pneumocystis PCP molecular epidemiology typing methods perspective |
url |
https://wwwnc.cdc.gov/eid/article/10/10/03-0981_article |
work_keys_str_mv |
AT charlesbenbeard straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia AT patriciaroux straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia AT gillesnevez straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia AT philippemhauser straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia AT josephakovacs straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia AT thomasrunnasch straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia AT bettinalundgren straintypingmethodsandmolecularepidemiologyofpneumocystispneumonia |
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