miRNA profiling of circulating EpCAM+ extracellular vesicles: promising biomarkers of colorectal cancer

miRNA profiling of circulating EpCAM+ extracellular vesicles: promising biomarkers of colorectal cancer

Cancer cells secrete small membranous extracellular vesicles (EVs) into their microenvironment and circulation. These contain biomolecules, including proteins and microRNAs (miRNAs). Both circulating EVs and miRNAs have received much attention as biomarker candidates for non-invasive diagnostics. He...

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Bibliographic Details
Main Authors: Marie Stampe Ostenfeld, Steffen Grann Jensen, Dennis Kjølhede Jeppesen, Lise-Lotte Christensen, Stine Buch Thorsen, Jan Stenvang, Michael Lykke Hvam, Anni Thomsen, Peter Mouritzen, Mads Heilskov Rasmussen, Hans Jørgen Nielsen, Torben Falck Ørntoft, Claus Lindbjerg Andersen
Format: Article
Language:English
Published: Taylor & Francis Group 2016-08-01
Series:Journal of Extracellular Vesicles
Subjects:
colorectal cancer
epithelial-derived extracellular vesicles
isolation
immunoaffinity
blood-based CRC detection
non-invasive biomarkers
microRNA
Online Access:http://www.journalofextracellularvesicles.net/index.php/jev/article/view/31488/pdf_72

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