Regulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemia.

Increased expression of endothelin receptor type B (ETBR), a vasoactive receptor, has recently been implied in the reduced cerebral blood flow and exacerbated neuronal damage after ischemia-reperfusion (I/R). The study explores the regulatory mechanisms of ETBR to identify drug targets to restore no...

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Bibliographic Details
Main Authors: Anne-Sofie Grell, Rushani Thigarajah, Lars Edvinsson, Ajoy Kumar Samraj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4257531?pdf=render

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