Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection.

Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection.

Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that successfully initiate infection, and also those that drive progression to chronicity is instrumental for understanding pathogenesis and vaccine design....

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Bibliographic Details
Main Authors: Rowena A Bull, Fabio Luciani, Kerensa McElroy, Silvana Gaudieri, Son T Pham, Abha Chopra, Barbara Cameron, Lisa Maher, Gregory J Dore, Peter A White, Andrew R Lloyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21912520/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21912520/?tool=EBI

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