DEBATE-statistical analysis plans for observational studies

Abstract Background All clinical research benefits from transparency and validity. Transparency and validity of studies may increase by prospective registration of protocols and by publication of statistical analysis plans (SAPs) before data have been accessed to discern data-driven analyses from pr...

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Bibliographic Details
Main Authors: Bart Hiemstra, Frederik Keus, Jørn Wetterslev, Christian Gluud, Iwan C. C. van der Horst
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medical Research Methodology
Online Access:https://doi.org/10.1186/s12874-019-0879-5