Interaction of Sirtuin 1 (SIRT1) candidate longevity gene and particulate matter (PM2.5) on all-cause mortality: a longitudinal cohort study in China

Abstract Background The SIRT1 gene was associated with the lifespan in several organisms through inflammatory and oxidative stress pathways. Long-term air particulate matter (PM) is detrimental to health through the same pathways. Methods We used the Chinese Longitudinal Healthy Longevity Survey (CL...

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Bibliographic Details
Main Authors: Yao Yao, Linxin Liu, Guang Guo, Yi Zeng, John S. Ji
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Environmental Health
Subjects:
Online Access:https://doi.org/10.1186/s12940-021-00718-x