Increased Expression of the NOD-like Receptor Family, Pyrin Domain Containing 3 Inflammasome in Dermatomyositis and Polymyositis is a Potential Contributor to Their Pathogenesis

Increased Expression of the NOD-like Receptor Family, Pyrin Domain Containing 3 Inflammasome in Dermatomyositis and Polymyositis is a Potential Contributor to Their Pathogenesis

Background: Dermatomyositis (DM) and polymyositis (PM) are common inflammatory myopathies whose immunopathogenic mechanisms remain poorly understood. The NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome is a type of cytoplasmic multiprotein inflammasome and is responsible for...

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Bibliographic Details
Main Authors: Xi Yin, Gen-Cheng Han, Xing-Wei Jiang, Qiang Shi, Chuan-Qiang Pu
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Autoimmunity; Dermatomyositis; NOD-like Receptor Family
Pyrin Domain Containing 3 Inflammasome; Polymyositis
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=9;spage=1047;epage=1052;aulast=Yin

Internet

http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=9;spage=1047;epage=1052;aulast=Yin

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