Molecular modeling-based evaluation of hTLR10 and identification of potential ligands in Toll-like receptor signaling.

Toll-like receptors (TLRs) are pattern recognition receptors that recognize pathogens based on distinct molecular signatures. The human (h)TLR1, 2, 6 and 10 belong to the hTLR1 subfamilies, which are localized in the extracellular regions and activated in response to diverse ligand molecules. Due to...

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Bibliographic Details
Main Authors: Rajiv Gandhi Govindaraj, Balachandran Manavalan, Gwang Lee, Sangdun Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2943521?pdf=render