Assessing Prion Infectivity of Human Urine in Sporadic Creutzfeldt-Jakob Disease

Assessing Prion Infectivity of Human Urine in Sporadic Creutzfeldt-Jakob Disease

Prion diseases are neurodegenerative conditions associated with a misfolded and infectious protein, scrapie prion protein (PrPSc). PrPSc propagate prion diseases within and between species and thus pose risks to public health. Prion infectivity or PrPSc presence has been demonstrated in urine of exp...

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Bibliographic Details
Main Authors: Silvio Notari, Liuting Qing, Maurizio Pocchiari, Ayuna Dagdanova, Kristin Hatcher, Arend Dogterom, Jose F. Groisman, Ib Bo Lumholtz, Maria Puopolo, Corinne Lasmezas, Shu G. Chen, Qingzhong Kong, Pierluigi Gambetti
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2012-01-01
Series:Emerging Infectious Diseases
Subjects:
prions
prions and related diseases
Creutzfeld-Jakob disease
neurodegenerative diseases
transmissible spongiform encephalopathy
infectivity
Online Access:https://wwwnc.cdc.gov/eid/article/18/1/11-0589_article

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