A Mechanism for Statin-Induced Susceptibility to Myopathy

A Mechanism for Statin-Induced Susceptibility to Myopathy

Summary: This study aimed to identify a mechanism for statin-induced myopathy that explains its prevalence and selectivity for skeletal muscle, and to understand its interaction with moderate exercise. Statin-associated adverse muscle symptoms reduce adherence to statin therapy; this limits the effe...

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Bibliographic Details
Main Authors: Sabine Lotteau, PhD, Niklas Ivarsson, PhD, Zhaokang Yang, PhD, Damien Restagno, PhD, John Colyer, PhD, Philip Hopkins, MD, Andrew Weightman, PhD, Koichi Himori, MSc, Takashi Yamada, PhD, Joseph Bruton, PhD, Derek Steele, PhD, Håkan Westerblad, MD, PhD, Sarah Calaghan, PhD
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19301317

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http://www.sciencedirect.com/science/article/pii/S2452302X19301317

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