Whole Transcriptome Analysis Reveals Heterogeneity in B Cell Memory Populations in Patients With Juvenile Idiopathic Arthritis-Associated Uveitis

Whole Transcriptome Analysis Reveals Heterogeneity in B Cell Memory Populations in Patients With Juvenile Idiopathic Arthritis-Associated Uveitis

PurposePatients with juvenile idiopathic arthritis (JIA) are prone to developing chronic anterior uveitis (JIA-U+). Although several risk factors for JIA-U+ have been identified, the underlying etiology is poorly understood. Histopathological studies demonstrate B cell infiltrates in eye tissues of...

Full description

Bibliographic Details
Main Authors: Roos A. W. Wennink, Aridaman Pandit, Anne-Mieke J. W. Haasnoot, Sanne Hiddingh, Viera Kalinina Ayuso, Nico M. Wulffraat, Bas J. Vastert, Timothy R. D. J. Radstake, Joke H. de Boer, Jonas J. W. Kuiper
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
juvenile idiopathic arthritis
juvenile idiopathic arthritis associated uveitis
RNA sequencing
B cell
memory B cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02170/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02170/full

Similar Items