THE UBIQUITIN-PROTEASOME SYSTEM: POTENTIAL THERAPEUTIC TARGETS FOR ALZHEIMER’S DISEASE AND SPINAL CORD INJURY

THE UBIQUITIN-PROTEASOME SYSTEM: POTENTIAL THERAPEUTIC TARGETS FOR ALZHEIMER’S DISEASE AND SPINAL CORD INJURY

The ubiquitin-proteasome system (UPS) is a crucial protein degradation system in eukaryotes. Herein we will review advances in the understanding of the role of several proteins of the UPS in Alzheimer’s disease (AD) and functional recovery after spinal cord injury (SCI). The UPS consists of many fa...

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Bibliographic Details
Main Authors: Bing eGong, Miroslav eRadulovic, Maria Emilia Figueiredo-Pereira, Christopher eCardozo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Spinal Cord Injuries
Alzheimer's disease
Neuroregeneration
ubiquitin-proteasome system
beta-amyloid clearance.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00004/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00004/full

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